NMDAR
NMDAR(N-methyl-D-aspartate receptor) is a glutamate receptor and ion channel protein found in nerve cells. It is activated when glutamate and glycine (or D-serine) bind to it, and when activated it allows positively charged ions to flow through the cell membrane. The NMDA receptor is very important for controlling synaptic plasticity and memory function. The NMDAR is a specific type of ionotropic glutamate receptor.
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(S)-(+)-Ketamine hydrochloride是NMDA 受体 拮抗剂, Ketamine hydrochloride的对映体之一。
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(S)-(-)-HA-966是NMDA 拮抗剂/部分激动剂。
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(RS)-CPP是活性的 NMDA 拮抗剂。
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(RS)-(Tetrazol-5-yl)glycine是高活性的NMDA受体激动剂。
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(R)-CPP是活性的 NMDA 拮抗剂, (RS)-CPP活性更好的的对映体之一 。
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